K297-0492
TL;DR: K297-0492 (CAS 422533-71-9) is a chemical compound with molecular formula C25H24ClN3O2S and molecular weight 465.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(2-chlorophenyl)methylsulfanyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]quinazolin-4-amine
Also Known As: K297-0492, F6548-4578, 2-[(2-chlorophenyl)methylsulfanyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]quinazolin-4-amine, 2-{[(2-chlorophenyl)methyl]sulfanyl}-N-[2-(3,4-dimethoxyphenyl)ethyl]quinazolin-4-amine, 2-((2-chlorobenzyl)thio)-N-(3,4-dimethoxyphenethyl)quinazolin-4-amine
| Molecular Formula | C25H24ClN3O2S |
|---|---|
| Molecular Weight | 465.13 g/mol |
| LogP | 6.2473 |
| Topological Polar Surface Area | 56.27 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 465.12778 |
| Heavy Atoms | 32 |
| Complexity | 1218.9045 |
Chemical Identifiers
| CAS Number | 422533-71-9 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)CCNC2=NC(=NC3=CC=CC=C32)SCC4=CC=CC=C4Cl)OC |
Product Overview
K297-0492 (CAS 422533-71-9), with molecular formula C25H24ClN3O2S and molecular weight 465.13 g/mol. IUPAC: 2-[(2-chlorophenyl)methylsulfanyl]-N-[2-(3,4-dimethoxyphenyl)ethyl]quinazolin-4-amine.
Chemical Property Profile of K297-0492
Property Insights of K297-0492
The XLogP value of 6.2473 indicates that K297-0492 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.27 Ų, K297-0492 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, K297-0492 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of K297-0492?
The CAS number of K297-0492 is 422533-71-9.
What is the molecular formula of K297-0492?
The molecular formula of K297-0492 is C25H24ClN3O2S.
What is the molecular weight of K297-0492?
The molecular weight of K297-0492 is 465.13 g/mol.
Where can I buy K297-0492?
You can request a quote for K297-0492 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for K297-0492?
Yes, KEHONG BIO provides custom synthesis services for K297-0492 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.