Egfr/her2/cdk9-IN-3
TL;DR: Egfr/her2/cdk9-IN-3 (CAS 422276-47-9) is a chemical compound with molecular formula C24H21N3O4S2 and molecular weight 479.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[2-(4-oxo-2-phenacylsulfanylquinazolin-3-yl)ethyl]benzenesulfonamide
Also Known As: EGFR/HER2/CDK9-IN-3, 4-[2-(4-oxo-2-phenacylsulfanylquinazolin-3-yl)ethyl]benzenesulfonamide, 4-[2-(4-oxo-2-phenacylsulfanyl-quinazolin-3-yl)ethyl]benzenesulfonamide, 4-(2-(4-Oxo-2-((2-oxo-2-phenylethyl)thio)quinazolin-3(4H)-yl)ethyl)benzenesulfonamide
| Molecular Formula | C24H21N3O4S2 |
|---|---|
| Molecular Weight | 479.10 g/mol |
| LogP | 3.2616 |
| Topological Polar Surface Area | 112.12 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 479.09735 |
| Heavy Atoms | 33 |
| Complexity | 1465.6189 |
Chemical Identifiers
| CAS Number | 422276-47-9 |
|---|---|
| SMILES | C1=CC=C(C=C1)C(=O)CSC2=NC3=CC=CC=C3C(=O)N2CCC4=CC=C(C=C4)S(=O)(=O)N |
Product Overview
Egfr/her2/cdk9-IN-3 (CAS 422276-47-9), with molecular formula C24H21N3O4S2 and molecular weight 479.10 g/mol. IUPAC: 4-[2-(4-oxo-2-phenacylsulfanylquinazolin-3-yl)ethyl]benzenesulfonamide.
Chemical Property Profile of Egfr/her2/cdk9-IN-3
Property Insights of Egfr/her2/cdk9-IN-3
The XLogP value of 3.2616 indicates that Egfr/her2/cdk9-IN-3 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 112.12 Ų falls within the moderate polarity range, balancing permeability and solubility for Egfr/her2/cdk9-IN-3. Following Lipinski's Rule of Five, Egfr/her2/cdk9-IN-3 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Egfr/her2/cdk9-IN-3?
The CAS number of Egfr/her2/cdk9-IN-3 is 422276-47-9.
What is the molecular formula of Egfr/her2/cdk9-IN-3?
The molecular formula of Egfr/her2/cdk9-IN-3 is C24H21N3O4S2.
What is the molecular weight of Egfr/her2/cdk9-IN-3?
The molecular weight of Egfr/her2/cdk9-IN-3 is 479.10 g/mol.
Where can I buy Egfr/her2/cdk9-IN-3?
You can request a quote for Egfr/her2/cdk9-IN-3 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Egfr/her2/cdk9-IN-3?
Yes, KEHONG BIO provides custom synthesis services for Egfr/her2/cdk9-IN-3 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.