1-Chloro-1,1,2-trifluoroethane structure

1-Chloro-1,1,2-trifluoroethane

TL;DR: 1-Chloro-1,1,2-trifluoroethane (CAS 421-04-5) is a chemical compound with molecular formula C2H2ClF3 and molecular weight 117.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-chloro-1,1,2-trifluoroethane

Also Known As: 1-Chloro-1,1,2-trifluoroethane, Freon-133b, Fron-133b, Ethane, 1-chloro-1,1,2-trifluoro-, R 133b

CAS: 421-04-5
Molecular Formula C2H2ClF3
Molecular Weight 117.98 g/mol
LogP 1.7875
Topological Polar Surface Area 0.0 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 0
Rotatable Bonds 1
Exact Mass 117.97971
Heavy Atoms 6
Complexity 38.54808

Chemical Identifiers

CAS Number 421-04-5
SMILES C(C(F)(F)Cl)F

Product Overview

1-Chloro-1,1,2-trifluoroethane (CAS 421-04-5), with molecular formula C2H2ClF3 and molecular weight 117.98 g/mol. IUPAC: 1-chloro-1,1,2-trifluoroethane.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1-Chloro-1,1,2-trifluoroethane

XLogP
1.7875
TPSA (Topological Polar Surface Area)
0.0
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
0
Rotatable Bonds
1
Heavy Atoms
6
Complexity
38.54808
Exact Mass
117.97971
Monoisotopic Mass
117.97971
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-Chloro-1,1,2-trifluoroethane

The XLogP value of 1.7875 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-Chloro-1,1,2-trifluoroethane. With a topological polar surface area (TPSA) of 0.0 Ų, 1-Chloro-1,1,2-trifluoroethane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Chloro-1,1,2-trifluoroethane has 0 hydrogen bond donor(s) and 0 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-Chloro-1,1,2-trifluoroethane?

The CAS number of 1-Chloro-1,1,2-trifluoroethane is 421-04-5.

What is the molecular formula of 1-Chloro-1,1,2-trifluoroethane?

The molecular formula of 1-Chloro-1,1,2-trifluoroethane is C2H2ClF3.

What is the molecular weight of 1-Chloro-1,1,2-trifluoroethane?

The molecular weight of 1-Chloro-1,1,2-trifluoroethane is 117.98 g/mol.

Where can I buy 1-Chloro-1,1,2-trifluoroethane?

You can request a quote for 1-Chloro-1,1,2-trifluoroethane directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-Chloro-1,1,2-trifluoroethane?

Yes, KEHONG BIO provides custom synthesis services for 1-Chloro-1,1,2-trifluoroethane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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