2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide
TL;DR: 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide (CAS 420093-41-0) is a chemical compound with molecular formula C20H12ClFN2OS and molecular weight 382.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide
Also Known As: 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide, 2-(5-chloro-2-thienyl)-N-(2-fluorophenyl)-4-quinolinecarboxamide, [2-(5-chloro(2-thienyl))(4-quinolyl)]-N-(2-fluorophenyl)carboxamide
| Molecular Formula | C20H12ClFN2OS |
|---|---|
| Molecular Weight | 382.03 g/mol |
| LogP | 6.0081 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 382.0343 |
| Heavy Atoms | 26 |
| Complexity | 1125.7124 |
Chemical Identifiers
| CAS Number | 420093-41-0 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CC(=N2)C3=CC=C(S3)Cl)C(=O)NC4=CC=CC=C4F |
Product Overview
2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide (CAS 420093-41-0), with molecular formula C20H12ClFN2OS and molecular weight 382.03 g/mol. IUPAC: 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide.
Chemical Property Profile of 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide
Property Insights of 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide
The XLogP value of 6.0081 indicates that 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide?
The CAS number of 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide is 420093-41-0.
What is the molecular formula of 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide?
The molecular formula of 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide is C20H12ClFN2OS.
What is the molecular weight of 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide?
The molecular weight of 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide is 382.03 g/mol.
Where can I buy 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide?
You can request a quote for 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 2-(5-chlorothiophen-2-yl)-N-(2-fluorophenyl)quinoline-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.