![[2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone structure](/static/products/4200/420089-66-3.webp)
[2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone
TL;DR: [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone (CAS 420089-66-3) is a chemical compound with molecular formula C26H24ClN3OS and molecular weight 461.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone
Also Known As: [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone, 2-(5-chloro-2-thienyl)-4-{[4-(2,3-dimethylphenyl)-1-piperazinyl]carbonyl}quinoline, [2-(5-chlorothiophen-2-yl)quinolin-4-yl][4-(2,3-dimethylphenyl)piperazin-1-yl]methanone, 4-(2,3-dimethylphenyl)piperazinyl 2-(5-chloro(2-thienyl))(4-quinolyl) ketone
| Molecular Formula | C26H24ClN3OS |
|---|---|
| Molecular Weight | 461.13 g/mol |
| LogP | 6.19594 |
| Topological Polar Surface Area | 36.44 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 461.13287 |
| Heavy Atoms | 32 |
| Complexity | 1307.6785 |
Chemical Identifiers
| CAS Number | 420089-66-3 |
|---|---|
| SMILES | CC1=C(C(=CC=C1)N2CCN(CC2)C(=O)C3=CC(=NC4=CC=CC=C43)C5=CC=C(S5)Cl)C |
Product Overview
[2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone (CAS 420089-66-3), with molecular formula C26H24ClN3OS and molecular weight 461.13 g/mol. IUPAC: [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone.
Chemical Property Profile of [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone
Property Insights of [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone
The XLogP value of 6.19594 indicates that [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.44 Ų, [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone?
The CAS number of [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone is 420089-66-3.
What is the molecular formula of [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone?
The molecular formula of [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone is C26H24ClN3OS.
What is the molecular weight of [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone?
The molecular weight of [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone is 461.13 g/mol.
Where can I buy [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone?
You can request a quote for [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone?
Yes, KEHONG BIO provides custom synthesis services for [2-(5-chlorothiophen-2-yl)quinolin-4-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.