EGFR-IN-121
TL;DR: EGFR-IN-121 (CAS 418799-16-3) is a chemical compound with molecular formula C23H26N2O5 and molecular weight 410.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
propan-2-yl 4-(3-methoxy-4-phenylmethoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
Also Known As: EGFR-IN-121, propan-2-yl 4-[4-(benzyloxy)-3-methoxyphenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate, isopropyl 4-(4-(benzyloxy)-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate, propan-2-yl 4-(3-methoxy-4-phenylmethoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
| Molecular Formula | C23H26N2O5 |
|---|---|
| Molecular Weight | 410.18 g/mol |
| LogP | 3.8537 |
| Topological Polar Surface Area | 85.89 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 410.18417 |
| Heavy Atoms | 30 |
| Complexity | 953.32074 |
Chemical Identifiers
| CAS Number | 418799-16-3 |
|---|---|
| SMILES | CC1=C(C(NC(=O)N1)C2=CC(=C(C=C2)OCC3=CC=CC=C3)OC)C(=O)OC(C)C |
Product Overview
EGFR-IN-121 (CAS 418799-16-3), with molecular formula C23H26N2O5 and molecular weight 410.18 g/mol. IUPAC: propan-2-yl 4-(3-methoxy-4-phenylmethoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate.
Chemical Property Profile of EGFR-IN-121
Property Insights of EGFR-IN-121
The XLogP value of 3.8537 indicates that EGFR-IN-121 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.89 Ų falls within the moderate polarity range, balancing permeability and solubility for EGFR-IN-121. Following Lipinski's Rule of Five, EGFR-IN-121 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of EGFR-IN-121?
The CAS number of EGFR-IN-121 is 418799-16-3.
What is the molecular formula of EGFR-IN-121?
The molecular formula of EGFR-IN-121 is C23H26N2O5.
What is the molecular weight of EGFR-IN-121?
The molecular weight of EGFR-IN-121 is 410.18 g/mol.
Where can I buy EGFR-IN-121?
You can request a quote for EGFR-IN-121 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for EGFR-IN-121?
Yes, KEHONG BIO provides custom synthesis services for EGFR-IN-121 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.