5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone
TL;DR: 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone (CAS 418757-25-2) is a chemical compound with molecular formula C21H16N2O2 and molecular weight 328.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-methyl-4-(naphthalene-2-carbonyl)-2-phenyl-1H-pyrazol-3-one
Also Known As: J1.626.048G, 5-methyl-4-(naphthalene-2-carbonyl)-2-phenyl-1H-pyrazol-3-one, 5-hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone, (5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-naphthalenyl-Methanone, 1-Phenyl-3-methyl-4-(2-naphthylcarbonyl)-1H-pyrazole-5-ol
| Molecular Formula | C21H16N2O2 |
|---|---|
| Molecular Weight | 328.12 g/mol |
| LogP | 3.85822 |
| Topological Polar Surface Area | 54.86 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 328.1212 |
| Heavy Atoms | 25 |
| Complexity | 1137.4949 |
Chemical Identifiers
| CAS Number | 418757-25-2 |
|---|---|
| SMILES | CC1=C(C(=O)N(N1)C2=CC=CC=C2)C(=O)C3=CC4=CC=CC=C4C=C3 |
Product Overview
5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone (CAS 418757-25-2), with molecular formula C21H16N2O2 and molecular weight 328.12 g/mol. IUPAC: 5-methyl-4-(naphthalene-2-carbonyl)-2-phenyl-1H-pyrazol-3-one.
Chemical Property Profile of 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone
Property Insights of 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone
The XLogP value of 3.85822 indicates that 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.86 Ų, 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone?
The CAS number of 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone is 418757-25-2.
What is the molecular formula of 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone?
The molecular formula of 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone is C21H16N2O2.
What is the molecular weight of 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone?
The molecular weight of 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone is 328.12 g/mol.
Where can I buy 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone?
You can request a quote for 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone?
Yes, KEHONG BIO provides custom synthesis services for 5-Hydroxy-3-methyl-1-phenylpyrazol-4-yl 2-naphthyl ketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.