Aconifine structure

Aconifine

TL;DR: Aconifine (CAS 41849-35-8) is a chemical compound with molecular formula C34H47NO12 and molecular weight 661.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(1R,2S,3S,4R,5R,6S,7S,8S,9R,13R,14R,16S,17R,18R)-8-acetyloxy-11-ethyl-2,5,7,14-tetrahydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate

Also Known As: Aconifine, Nagarine, 10-Hydroxyaconitine, 10-Hydroxy aconitine, 10-OH-Aconitine

CAS: 41849-35-8
Molecular Formula C34H47NO12
Molecular Weight 661.31 g/mol
LogP -0.8
Topological Polar Surface Area 174.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 13
Rotatable Bonds 11
Exact Mass 661.3098
Heavy Atoms 47
Complexity 1260.0

Chemical Identifiers

CAS Number 41849-35-8
SMILES CCN1C[C@@]2([C@@H](C[C@@H]([C@@]34[C@@H]2[C@H]([C@@H](C31)[C@@]5([C@@H]6[C@]4(C[C@@]([C@@H]6OC(=O)C7=CC=CC=C7)([C@H]([C@@H]5O)OC)O)O)OC(=O)C)OC)OC)O)COC
InChIKey GMSKTJVHWUUOMY-UHBPHNCFSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Organic Building Blocks (1 patents) Pharmaceutical Intermediates (7 patents)

Product Overview

Aconifine (CAS 41849-35-8), with molecular formula C34H47NO12 and molecular weight 661.31 g/mol. IUPAC: [(1R,2S,3S,4R,5R,6S,7S,8S,9R,13R,14R,16S,17R,18R)-8-acetyloxy-11-ethyl-2,5,7,14-tetrahydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Aconifine

XLogP
-0.8
TPSA (Topological Polar Surface Area)
174.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
13
Rotatable Bonds
11
Heavy Atoms
47
Complexity
1260.0
Exact Mass
661.3098
Monoisotopic Mass
661.3098
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Aconifine

The XLogP value of -0.8 indicates that Aconifine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 174.0 Ų indicates high polarity, suggesting Aconifine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Aconifine has 4 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Aconifine?

The CAS number of Aconifine is 41849-35-8.

What is the molecular formula of Aconifine?

The molecular formula of Aconifine is C34H47NO12.

What is the molecular weight of Aconifine?

The molecular weight of Aconifine is 661.31 g/mol.

Where can I buy Aconifine?

You can request a quote for Aconifine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Aconifine?

Yes, KEHONG BIO provides custom synthesis services for Aconifine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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