SIR 114 structure

SIR 114

TL;DR: SIR 114 (CAS 41659-20-5) is a chemical compound with molecular formula C22H23Cl2N and molecular weight 371.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5'-chloro-N,N-dimethylspiro[cyclohex-2-ene-4,2'-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,9,11,13-heptaene]-1-amine;hydrochloride

Also Known As: SIR 114, 3-Chloro-N,N-dimethylspiro(5H-dibenzo(a,d)cycloheptene-5,1'-cyclohex-2'-en)-4'-amine, Spiro(5H-dibenzo(a,d)cycloheptene-5,1'-cyclohex-2'-en)-4'-amine, 3-chloro-N,N-dimethyl-, hydrochloride, 3'-Chloro-N,N-dimethylspiro[cyclohex-2-ene-1,5'-dibenzo[a,d][7]annulen]-4-amine--hydrogen chloride (1/1), Spiro[2-cyclohexene-1,5'-[5H]dibenzo[a,d]cyclohepten]-4-amine, 3'-chloro-N,N-dimethyl-, hydrochloride

CAS: 41659-20-5
Molecular Formula C22H23Cl2N
Molecular Weight 371.12 g/mol
LogP 5.8119
Topological Polar Surface Area 3.24 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 1
Exact Mass 371.12076
Heavy Atoms 25
Complexity 837.6709

Chemical Identifiers

CAS Number 41659-20-5
SMILES CN(C)C1CCC2(C=C1)C3=CC=CC=C3C=CC4=C2C=C(C=C4)Cl.Cl

Product Overview

SIR 114 (CAS 41659-20-5), with molecular formula C22H23Cl2N and molecular weight 371.12 g/mol. IUPAC: 5'-chloro-N,N-dimethylspiro[cyclohex-2-ene-4,2'-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,9,11,13-heptaene]-1-amine;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of SIR 114

XLogP
5.8119
TPSA (Topological Polar Surface Area)
3.24
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
1
Heavy Atoms
25
Complexity
837.6709
Exact Mass
371.12076
Monoisotopic Mass
371.12076
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of SIR 114

The XLogP value of 5.8119 indicates that SIR 114 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.24 Ų, SIR 114 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, SIR 114 has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of SIR 114?

The CAS number of SIR 114 is 41659-20-5.

What is the molecular formula of SIR 114?

The molecular formula of SIR 114 is C22H23Cl2N.

What is the molecular weight of SIR 114?

The molecular weight of SIR 114 is 371.12 g/mol.

Where can I buy SIR 114?

You can request a quote for SIR 114 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for SIR 114?

Yes, KEHONG BIO provides custom synthesis services for SIR 114 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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