7-Chlorocamptothecin
TL;DR: 7-Chlorocamptothecin (CAS 41646-05-3) is a chemical compound with molecular formula C20H15ClN2O4 and molecular weight 382.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(19S)-10-chloro-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Also Known As: 7-Chlorocamptothecin, NCI60_001992, (4S)-11-Chloro-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 11-Chloro-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 1H-Pyrano[3',7]indolizino[1,2-b]quinoline-3,14(4H,12H)- dione, 11-chloro-4-ethyl-4-hydroxy-, (S)-
| Molecular Formula | C20H15ClN2O4 |
|---|---|
| Molecular Weight | 382.07 g/mol |
| LogP | 1.6 |
| Topological Polar Surface Area | 79.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 382.07202 |
| Heavy Atoms | 27 |
| Complexity | 778.0 |
Chemical Identifiers
| CAS Number | 41646-05-3 |
|---|---|
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)Cl)O |
| InChIKey | KUAKYFCHUDSMNU-FQEVSTJZSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
7-Chlorocamptothecin (CAS 41646-05-3), with molecular formula C20H15ClN2O4 and molecular weight 382.07 g/mol. IUPAC: (19S)-10-chloro-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 7-Chlorocamptothecin
Property Insights of 7-Chlorocamptothecin
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 7-Chlorocamptothecin. The TPSA of 79.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-Chlorocamptothecin. Following Lipinski's Rule of Five, 7-Chlorocamptothecin has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Chlorocamptothecin?
The CAS number of 7-Chlorocamptothecin is 41646-05-3.
What is the molecular formula of 7-Chlorocamptothecin?
The molecular formula of 7-Chlorocamptothecin is C20H15ClN2O4.
What is the molecular weight of 7-Chlorocamptothecin?
The molecular weight of 7-Chlorocamptothecin is 382.07 g/mol.
Where can I buy 7-Chlorocamptothecin?
You can request a quote for 7-Chlorocamptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Chlorocamptothecin?
Yes, KEHONG BIO provides custom synthesis services for 7-Chlorocamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.