Butorphan
TL;DR: Butorphan (CAS 4163-26-2) is a chemical compound with molecular formula C21H29NO and molecular weight 311.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R,9R,10R)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
Also Known As: butorphan, (-)-butorphan, MCL-101 free base, N-(Cyclobutylmethyl)morphinan-3-ol, Morphinan-3-ol, 17-(cyclobutylmethyl)-
| Molecular Formula | C21H29NO |
|---|---|
| Molecular Weight | 311.22 g/mol |
| LogP | 4.2507 |
| Topological Polar Surface Area | 23.47 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 311.2249 |
| Heavy Atoms | 23 |
| Complexity | 607.8592 |
Chemical Identifiers
| CAS Number | 4163-26-2 |
|---|---|
| SMILES | C1CC[C@@]23CCN([C@@H]([C@@H]2C1)CC4=C3C=C(C=C4)O)CC5CCC5 |
Product Overview
Butorphan (CAS 4163-26-2), with molecular formula C21H29NO and molecular weight 311.22 g/mol. IUPAC: (1R,9R,10R)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol.
Chemical Property Profile of Butorphan
Property Insights of Butorphan
The XLogP value of 4.2507 indicates that Butorphan is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.47 Ų, Butorphan exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Butorphan has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Butorphan?
The CAS number of Butorphan is 4163-26-2.
What is the molecular formula of Butorphan?
The molecular formula of Butorphan is C21H29NO.
What is the molecular weight of Butorphan?
The molecular weight of Butorphan is 311.22 g/mol.
Where can I buy Butorphan?
You can request a quote for Butorphan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Butorphan?
Yes, KEHONG BIO provides custom synthesis services for Butorphan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.