3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide
TL;DR: 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide (CAS 414905-09-2) is a chemical compound with molecular formula C10H8F6N2O3S and molecular weight 350.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3,3,3-trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propanamide
Also Known As: Hdm2 E3 Ligase Inhibitor, Hdm2 E3 ligase inhibitor 1, J1.838.817K, AB00079619-01, 2,2-Di(trifluoromethyl)-4 -sulfamoylacetoanilide
| Molecular Formula | C10H8F6N2O3S |
|---|---|
| Molecular Weight | 350.02 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 97.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 3 |
| Exact Mass | 350.016 |
| Heavy Atoms | 22 |
| Complexity | 488.0 |
Chemical Identifiers
| CAS Number | 414905-09-2 |
|---|---|
| SMILES | C1=CC(=CC=C1NC(=O)C(C(F)(F)F)C(F)(F)F)S(=O)(=O)N |
| InChIKey | SKFRRPUNXSXVKN-UHFFFAOYSA-N |
Product Overview
3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide (CAS 414905-09-2), with molecular formula C10H8F6N2O3S and molecular weight 350.02 g/mol. IUPAC: 3,3,3-trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propanamide.
Chemical Property Profile of 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide
Property Insights of 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide. The TPSA of 97.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide. Following Lipinski's Rule of Five, 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide has 2 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide?
The CAS number of 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide is 414905-09-2.
What is the molecular formula of 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide?
The molecular formula of 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide is C10H8F6N2O3S.
What is the molecular weight of 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide?
The molecular weight of 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide is 350.02 g/mol.
Where can I buy 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide?
You can request a quote for 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide?
Yes, KEHONG BIO provides custom synthesis services for 3,3,3-Trifluoro-N-(4-sulfamoylphenyl)-2-(trifluoromethyl)propionamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.