N-Desmethylgalantamine
TL;DR: N-Desmethylgalantamine (CAS 41303-52-0) is a chemical compound with molecular formula C16H19NO3 and molecular weight 273.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol
Also Known As: Norgalanthamine, N-Desmethyl Galanthamine, N-Norgalanthamine, Norgalantamine, N-Desmethylgalantamine
| Molecular Formula | C16H19NO3 |
|---|---|
| Molecular Weight | 273.14 g/mol |
| LogP | 1.5081 |
| Topological Polar Surface Area | 50.72 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 273.1365 |
| Heavy Atoms | 20 |
| Complexity | 583.3299 |
Chemical Identifiers
| CAS Number | 41303-52-0 |
|---|---|
| SMILES | COC1=C2C3=C(CNCC[C@]34C=C[C@@H](C[C@@H]4O2)O)C=C1 |
Product Overview
N-Desmethylgalantamine (CAS 41303-52-0), with molecular formula C16H19NO3 and molecular weight 273.14 g/mol. IUPAC: (1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol.
Chemical Property Profile of N-Desmethylgalantamine
Property Insights of N-Desmethylgalantamine
The XLogP value of 1.5081 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-Desmethylgalantamine. With a topological polar surface area (TPSA) of 50.72 Ų, N-Desmethylgalantamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-Desmethylgalantamine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Desmethylgalantamine?
The CAS number of N-Desmethylgalantamine is 41303-52-0.
What is the molecular formula of N-Desmethylgalantamine?
The molecular formula of N-Desmethylgalantamine is C16H19NO3.
What is the molecular weight of N-Desmethylgalantamine?
The molecular weight of N-Desmethylgalantamine is 273.14 g/mol.
Where can I buy N-Desmethylgalantamine?
You can request a quote for N-Desmethylgalantamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Desmethylgalantamine?
Yes, KEHONG BIO provides custom synthesis services for N-Desmethylgalantamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.