N-(4-tert-butylthiazol-2-yl)quinolin-5-amine
TL;DR: N-(4-tert-butylthiazol-2-yl)quinolin-5-amine (CAS 412008-34-5) is a chemical compound with molecular formula C16H17N3S and molecular weight 283.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-tert-butyl-N-quinolin-5-yl-1,3-thiazol-2-amine
Also Known As: N-(4-tert-butylthiazol-2-yl)quinolin-5-amine, N-(4-tert-butyl-1,3-thiazol-2-yl)quinolin-5-amine, N-[4-(1,1-dimethylethyl)-2-thiazolyl]-5-quinolinamine
| Molecular Formula | C16H17N3S |
|---|---|
| Molecular Weight | 283.11 g/mol |
| LogP | 4.7324 |
| Topological Polar Surface Area | 37.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 283.11432 |
| Heavy Atoms | 20 |
| Complexity | 735.3118 |
Chemical Identifiers
| CAS Number | 412008-34-5 |
|---|---|
| SMILES | CC(C)(C)C1=CSC(=N1)NC2=CC=CC3=C2C=CC=N3 |
Product Overview
N-(4-tert-butylthiazol-2-yl)quinolin-5-amine (CAS 412008-34-5), with molecular formula C16H17N3S and molecular weight 283.11 g/mol. IUPAC: 4-tert-butyl-N-quinolin-5-yl-1,3-thiazol-2-amine.
Chemical Property Profile of N-(4-tert-butylthiazol-2-yl)quinolin-5-amine
Property Insights of N-(4-tert-butylthiazol-2-yl)quinolin-5-amine
The XLogP value of 4.7324 indicates that N-(4-tert-butylthiazol-2-yl)quinolin-5-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.81 Ų, N-(4-tert-butylthiazol-2-yl)quinolin-5-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4-tert-butylthiazol-2-yl)quinolin-5-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-tert-butylthiazol-2-yl)quinolin-5-amine?
The CAS number of N-(4-tert-butylthiazol-2-yl)quinolin-5-amine is 412008-34-5.
What is the molecular formula of N-(4-tert-butylthiazol-2-yl)quinolin-5-amine?
The molecular formula of N-(4-tert-butylthiazol-2-yl)quinolin-5-amine is C16H17N3S.
What is the molecular weight of N-(4-tert-butylthiazol-2-yl)quinolin-5-amine?
The molecular weight of N-(4-tert-butylthiazol-2-yl)quinolin-5-amine is 283.11 g/mol.
Where can I buy N-(4-tert-butylthiazol-2-yl)quinolin-5-amine?
You can request a quote for N-(4-tert-butylthiazol-2-yl)quinolin-5-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-tert-butylthiazol-2-yl)quinolin-5-amine?
Yes, KEHONG BIO provides custom synthesis services for N-(4-tert-butylthiazol-2-yl)quinolin-5-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.