5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide
TL;DR: 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide (CAS 411207-61-9) is a chemical compound with molecular formula C10H6ClF2NO2S2 and molecular weight 308.95 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide
Also Known As: 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide, 3'-Nitro-biphenyl-4-carbaldehyde, (2,4-difluorophenyl)[(5-chloro(2-thienyl))sulfonyl]amine, 5-CHLORO-N-(2,4-DIFLUOROPHENYL)-2-THIOPHENESULFONAMIDE
| Molecular Formula | C10H6ClF2NO2S2 |
|---|---|
| Molecular Weight | 308.95 g/mol |
| LogP | 3.4805 |
| Topological Polar Surface Area | 46.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 308.94965 |
| Heavy Atoms | 18 |
| Complexity | 684.93616 |
Chemical Identifiers
| CAS Number | 411207-61-9 |
|---|---|
| SMILES | C1=CC(=C(C=C1F)F)NS(=O)(=O)C2=CC=C(S2)Cl |
Product Overview
5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide (CAS 411207-61-9), with molecular formula C10H6ClF2NO2S2 and molecular weight 308.95 g/mol. IUPAC: 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide.
Chemical Property Profile of 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide
Property Insights of 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide
The XLogP value of 3.4805 indicates that 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.17 Ų, 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide?
The CAS number of 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide is 411207-61-9.
What is the molecular formula of 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide?
The molecular formula of 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide is C10H6ClF2NO2S2.
What is the molecular weight of 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide?
The molecular weight of 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide is 308.95 g/mol.
Where can I buy 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide?
You can request a quote for 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide?
Yes, KEHONG BIO provides custom synthesis services for 5-chloro-N-(2,4-difluorophenyl)thiophene-2-sulfonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.