21-Hydroxy-20-methylpregn-4-en-3-one structure

21-Hydroxy-20-methylpregn-4-en-3-one

TL;DR: 21-Hydroxy-20-methylpregn-4-en-3-one (CAS 40736-33-2) is a chemical compound with molecular formula C22H34O2 and molecular weight 330.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,9S,10R,13S,14S,17R)-17-(1-hydroxypropan-2-yl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Also Known As: 21-Hydroxy-20-methylpregn-4-en-3-one, Progesterone Impurity 25, Progesterone Impurity 34, EINECS 262-543-1, 20-hydroxymethyl-4-pregnen-3-one

CAS: 40736-33-2
Molecular Formula C22H34O2
Molecular Weight 330.26 g/mol
LogP 4.7629
Topological Polar Surface Area 37.3 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 2
Exact Mass 330.2559
Heavy Atoms 24
Complexity 564.3172

Chemical Identifiers

CAS Number 40736-33-2
SMILES CC(CO)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

Product Overview

21-Hydroxy-20-methylpregn-4-en-3-one (CAS 40736-33-2), with molecular formula C22H34O2 and molecular weight 330.26 g/mol. IUPAC: (8S,9S,10R,13S,14S,17R)-17-(1-hydroxypropan-2-yl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 21-Hydroxy-20-methylpregn-4-en-3-one

XLogP
4.7629
TPSA (Topological Polar Surface Area)
37.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
24
Complexity
564.3172
Exact Mass
330.2559
Monoisotopic Mass
330.2559
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 21-Hydroxy-20-methylpregn-4-en-3-one

The XLogP value of 4.7629 indicates that 21-Hydroxy-20-methylpregn-4-en-3-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 21-Hydroxy-20-methylpregn-4-en-3-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 21-Hydroxy-20-methylpregn-4-en-3-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 21-Hydroxy-20-methylpregn-4-en-3-one?

The CAS number of 21-Hydroxy-20-methylpregn-4-en-3-one is 40736-33-2.

What is the molecular formula of 21-Hydroxy-20-methylpregn-4-en-3-one?

The molecular formula of 21-Hydroxy-20-methylpregn-4-en-3-one is C22H34O2.

What is the molecular weight of 21-Hydroxy-20-methylpregn-4-en-3-one?

The molecular weight of 21-Hydroxy-20-methylpregn-4-en-3-one is 330.26 g/mol.

Where can I buy 21-Hydroxy-20-methylpregn-4-en-3-one?

You can request a quote for 21-Hydroxy-20-methylpregn-4-en-3-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 21-Hydroxy-20-methylpregn-4-en-3-one?

Yes, KEHONG BIO provides custom synthesis services for 21-Hydroxy-20-methylpregn-4-en-3-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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