BMS 275183
TL;DR: BMS 275183 (CAS 406911-32-8) is a chemical compound with molecular formula C43H59NO15 and molecular weight 829.39 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-4,4-dimethyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
Also Known As: BMS 275183, J2.443.989E, (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Bis(acetyloxy)-15-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4,4-dimethylpentanoyl}oxy)-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0~3,10~.0~4,7~]heptadec-13-en-2-yl benzoate, (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-4,4-dimethylpentanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate, (2R,3S)-2-Hydroxy-3-[(tert-butyloxycarbonyl)amino]-4,4-dimethylpentanoic acid (1S)-1,7beta-dihydroxy-2alpha-(benzoyloxy)-4,10beta-diacetoxy-9-oxo-5beta,20-epoxytaxa-11-ene-13alpha-yl ester
| Molecular Formula | C43H59NO15 |
|---|---|
| Molecular Weight | 829.39 g/mol |
| LogP | 3.5038 |
| Topological Polar Surface Area | 230.52 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 8 |
| Exact Mass | 829.3885 |
| Heavy Atoms | 59 |
| Complexity | 1895.034 |
Chemical Identifiers
| CAS Number | 406911-32-8 |
|---|---|
| SMILES | CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C(C)(C)C)NC(=O)OC(C)(C)C)O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)OC(=O)C |
Product Overview
BMS 275183 (CAS 406911-32-8), with molecular formula C43H59NO15 and molecular weight 829.39 g/mol. IUPAC: [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-4,4-dimethyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate.
Chemical Property Profile of BMS 275183
Property Insights of BMS 275183
The XLogP value of 3.5038 indicates that BMS 275183 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 230.52 Ų indicates high polarity, suggesting BMS 275183 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, BMS 275183 has 4 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of BMS 275183?
The CAS number of BMS 275183 is 406911-32-8.
What is the molecular formula of BMS 275183?
The molecular formula of BMS 275183 is C43H59NO15.
What is the molecular weight of BMS 275183?
The molecular weight of BMS 275183 is 829.39 g/mol.
Where can I buy BMS 275183?
You can request a quote for BMS 275183 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for BMS 275183?
Yes, KEHONG BIO provides custom synthesis services for BMS 275183 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.