Piprofurol structure

Piprofurol

TL;DR: Piprofurol (CAS 40680-87-3) is a chemical compound with molecular formula C26H33NO6 and molecular weight 455.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[3-[4,7-dimethoxy-6-(2-piperidin-1-ylethoxy)-1-benzofuran-5-yl]-3-hydroxypropyl]phenol

Also Known As: Piprofurol, Piprofurolum, Piprofurol [INN], Piprofurolum [INN-Latin], 5-20-02-00137 (Beilstein Handbook Reference)

CAS: 40680-87-3
Molecular Formula C26H33NO6
Molecular Weight 455.23 g/mol
LogP 4.2
Topological Polar Surface Area 84.5 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 10
Exact Mass 455.23077
Heavy Atoms 33
Complexity 565.0

Chemical Identifiers

CAS Number 40680-87-3
SMILES COC1=C(C(=C(C2=C1C=CO2)OC)OCCN3CCCCC3)C(CCC4=CC=C(C=C4)O)O
InChIKey LIAPJIQUUKLLDZ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (8 patents) Pharmaceutical Intermediates (21 patents)

Product Overview

Piprofurol (CAS 40680-87-3), with molecular formula C26H33NO6 and molecular weight 455.23 g/mol. IUPAC: 4-[3-[4,7-dimethoxy-6-(2-piperidin-1-ylethoxy)-1-benzofuran-5-yl]-3-hydroxypropyl]phenol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Piprofurol

XLogP
4.2
TPSA (Topological Polar Surface Area)
84.5
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
10
Heavy Atoms
33
Complexity
565.0
Exact Mass
455.23077
Monoisotopic Mass
455.23077
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Piprofurol

The XLogP value of 4.2 indicates that Piprofurol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Piprofurol. Following Lipinski's Rule of Five, Piprofurol has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Piprofurol?

The CAS number of Piprofurol is 40680-87-3.

What is the molecular formula of Piprofurol?

The molecular formula of Piprofurol is C26H33NO6.

What is the molecular weight of Piprofurol?

The molecular weight of Piprofurol is 455.23 g/mol.

Where can I buy Piprofurol?

You can request a quote for Piprofurol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Piprofurol?

Yes, KEHONG BIO provides custom synthesis services for Piprofurol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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