2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether structure

2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether

TL;DR: 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether (CAS 405-44-7) is a chemical compound with molecular formula C8H5ClF3NO3 and molecular weight 254.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(2-chloro-1,1,2-trifluoroethoxy)-4-nitrobenzene

Also Known As: 1-(2-chloro-1,1,2-trifluoroethoxy)-4-nitrobenzene, 2-chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether, 4-(2-Chloro-1,1,2-trifluoroethoxy)-nitrobenzene, 1-(2-chloro-1,1,2-trifluoro-ethoxy)-4-nitro-benzene, Benzene, 1-(2-chloro-1,1,2-trifluoroethoxy)-4-nitro-

CAS: 405-44-7
Molecular Formula C8H5ClF3NO3
Molecular Weight 254.99 g/mol
LogP 3.1008
Topological Polar Surface Area 52.37 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 254.99101
Heavy Atoms 16
Complexity 382.61984

Chemical Identifiers

CAS Number 405-44-7
SMILES C1=CC(=CC=C1[N+](=O)[O-])OC(C(F)Cl)(F)F

Product Overview

2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether (CAS 405-44-7), with molecular formula C8H5ClF3NO3 and molecular weight 254.99 g/mol. IUPAC: 1-(2-chloro-1,1,2-trifluoroethoxy)-4-nitrobenzene.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether

XLogP
3.1008
TPSA (Topological Polar Surface Area)
52.37
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
16
Complexity
382.61984
Exact Mass
254.99101
Monoisotopic Mass
254.99101
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether

The XLogP value of 3.1008 indicates that 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.37 Ų, 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether?

The CAS number of 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether is 405-44-7.

What is the molecular formula of 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether?

The molecular formula of 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether is C8H5ClF3NO3.

What is the molecular weight of 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether?

The molecular weight of 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether is 254.99 g/mol.

Where can I buy 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether?

You can request a quote for 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether?

Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-1,1,2-trifluoroethyl 4-nitrophenyl ether and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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