帕比司他
TL;DR: 帕比司他 (CAS 404950-80-7) is a chemical compound with molecular formula C21H23N3O2 and molecular weight 349.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
帕比司他
(E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide
Also Known As: Panobinostat, Faridak, Farydak, Panobinostat (LBH589), LBH589
| Molecular Formula | C21H23N3O2 |
|---|---|
| Molecular Weight | 349.18 g/mol |
| LogP | 3.32722 |
| Topological Polar Surface Area | 77.15 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 7 |
| Exact Mass | 349.17902 |
| Heavy Atoms | 26 |
| Complexity | 910.6558 |
Chemical Identifiers
| CAS Number | 404950-80-7 |
|---|---|
| SMILES | CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO |
Product Overview
帕比司他 (CAS 404950-80-7), with molecular formula C21H23N3O2 and molecular weight 349.18 g/mol. IUPAC: (E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide.
Chemical Property Profile of 帕比司他
Property Insights of 帕比司他
The XLogP value of 3.32722 indicates that 帕比司他 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.15 Ų falls within the moderate polarity range, balancing permeability and solubility for 帕比司他. Following Lipinski's Rule of Five, 帕比司他 has 4 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 帕比司他?
The CAS number of 帕比司他 is 404950-80-7.
What is the molecular formula of 帕比司他?
The molecular formula of 帕比司他 is C21H23N3O2.
What is the molecular weight of 帕比司他?
The molecular weight of 帕比司他 is 349.18 g/mol.
Where can I buy 帕比司他?
You can request a quote for 帕比司他 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 帕比司他?
Yes, KEHONG BIO provides custom synthesis services for 帕比司他 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.