4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one
TL;DR: 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 404911-39-3) is a chemical compound with molecular formula C23H14ClF2NO3 and molecular weight 425.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(3-fluorophenyl)-1-(4-fluorophenyl)pyrrolidine-2,3-dione
Also Known As: 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one, (4E)-4-[(4-chlorophenyl)(hydroxy)methylidene]-5-(3-fluorophenyl)-1-(4-fluorophenyl)pyrrolidine-2,3-dione, (4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(3-fluorophenyl)-1-(4-fluorophenyl)pyrrolidine-2,3-dione
| Molecular Formula | C23H14ClF2NO3 |
|---|---|
| Molecular Weight | 425.06 g/mol |
| LogP | 5.2445 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 425.06302 |
| Heavy Atoms | 30 |
| Complexity | 1173.8124 |
Chemical Identifiers
| CAS Number | 404911-39-3 |
|---|---|
| SMILES | C1=CC(=CC(=C1)F)C2/C(=C(/C3=CC=C(C=C3)Cl)\O)/C(=O)C(=O)N2C4=CC=C(C=C4)F |
Product Overview
4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 404911-39-3), with molecular formula C23H14ClF2NO3 and molecular weight 425.06 g/mol. IUPAC: (4E)-4-[(4-chlorophenyl)-hydroxymethylidene]-5-(3-fluorophenyl)-1-(4-fluorophenyl)pyrrolidine-2,3-dione.
Chemical Property Profile of 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one
Property Insights of 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one
The XLogP value of 5.2445 indicates that 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one?
The CAS number of 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one is 404911-39-3.
What is the molecular formula of 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one?
The molecular formula of 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one is C23H14ClF2NO3.
What is the molecular weight of 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one?
The molecular weight of 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one is 425.06 g/mol.
Where can I buy 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one?
You can request a quote for 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-chlorobenzoyl)-5-(3-fluorophenyl)-1-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.