N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine
TL;DR: N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine (CAS 404828-14-4) is a chemical compound with molecular formula C18H15N5 and molecular weight 301.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine
Also Known As: GSK-3 Inhibitor XIII, Palonosetron, GSK3 Inhibitor XIII, GSK3i XIII, GSK3i XIII?
| Molecular Formula | C18H15N5 |
|---|---|
| Molecular Weight | 301.13 g/mol |
| LogP | 4.07192 |
| Topological Polar Surface Area | 66.49 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 301.13275 |
| Heavy Atoms | 23 |
| Complexity | 959.4926 |
Chemical Identifiers
| CAS Number | 404828-14-4 |
|---|---|
| SMILES | CC1=CC(=NN1)NC2=NC(=NC3=CC=CC=C32)C4=CC=CC=C4 |
Product Overview
N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine (CAS 404828-14-4), with molecular formula C18H15N5 and molecular weight 301.13 g/mol. IUPAC: N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine.
Chemical Property Profile of N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine
Property Insights of N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine
The XLogP value of 4.07192 indicates that N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.49 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine. Following Lipinski's Rule of Five, N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine?
The CAS number of N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine is 404828-14-4.
What is the molecular formula of N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine?
The molecular formula of N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine is C18H15N5.
What is the molecular weight of N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine?
The molecular weight of N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine is 301.13 g/mol.
Where can I buy N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine?
You can request a quote for N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine?
Yes, KEHONG BIO provides custom synthesis services for N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.