Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide structure

Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide

TL;DR: Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide (CAS 404366-39-8) is a chemical compound with molecular formula C12H11NO3S and molecular weight 249.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(3-hydroxy-4-methoxyphenyl)thiophene-2-carboxamide

Also Known As: BAS 00720676, N-(3-hydroxy-4-methoxyphenyl)thiophene-2-carboxamide, Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide, 2-Thiophenecarboxamide, N-(3-hydroxy-4-methoxyphenyl)- (9CI)

CAS: 404366-39-8
Molecular Formula C12H11NO3S
Molecular Weight 249.05 g/mol
LogP 2.4
Topological Polar Surface Area 86.8 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 249.04596
Heavy Atoms 17
Complexity 274.0

Chemical Identifiers

CAS Number 404366-39-8
SMILES COC1=C(C=C(C=C1)NC(=O)C2=CC=CS2)O
InChIKey NTTYRHXFPFTUBX-UHFFFAOYSA-N

Product Overview

Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide (CAS 404366-39-8), with molecular formula C12H11NO3S and molecular weight 249.05 g/mol. IUPAC: N-(3-hydroxy-4-methoxyphenyl)thiophene-2-carboxamide.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide

XLogP
2.4
TPSA (Topological Polar Surface Area)
86.8
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
17
Complexity
274.0
Exact Mass
249.04596
Monoisotopic Mass
249.04596
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide

The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide. The TPSA of 86.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide. Following Lipinski's Rule of Five, Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide?

The CAS number of Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide is 404366-39-8.

What is the molecular formula of Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide?

The molecular formula of Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide is C12H11NO3S.

What is the molecular weight of Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide?

The molecular weight of Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide is 249.05 g/mol.

Where can I buy Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide?

You can request a quote for Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide?

Yes, KEHONG BIO provides custom synthesis services for Thiophene-2-carboxylic acid (3-hydroxy-4-methoxy-phenyl)-amide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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