K289-0144
TL;DR: K289-0144 (CAS 403728-99-4) is a chemical compound with molecular formula C22H23N3O5S and molecular weight 441.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 2-[3-[4-(2-methoxyethylcarbamoyl)phenyl]-4-oxoquinazolin-2-yl]sulfanylacetate
Also Known As: K289-0144, F0912-3550, ethyl 2-[(3-{4-[(2-methoxyethyl)carbamoyl]phenyl}-4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]acetate, ethyl 2-[3-[4-(2-methoxyethylcarbamoyl)phenyl]-4-oxoquinazolin-2-yl]sulfanylacetate, ethyl 2-((3-(4-((2-methoxyethyl)carbamoyl)phenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetate
| Molecular Formula | C22H23N3O5S |
|---|---|
| Molecular Weight | 441.14 g/mol |
| LogP | 2.4171 |
| Topological Polar Surface Area | 99.52 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 9 |
| Exact Mass | 441.13583 |
| Heavy Atoms | 31 |
| Complexity | 1128.1897 |
Chemical Identifiers
| CAS Number | 403728-99-4 |
|---|---|
| SMILES | CCOC(=O)CSC1=NC2=CC=CC=C2C(=O)N1C3=CC=C(C=C3)C(=O)NCCOC |
Product Overview
K289-0144 (CAS 403728-99-4), with molecular formula C22H23N3O5S and molecular weight 441.14 g/mol. IUPAC: ethyl 2-[3-[4-(2-methoxyethylcarbamoyl)phenyl]-4-oxoquinazolin-2-yl]sulfanylacetate.
Chemical Property Profile of K289-0144
Property Insights of K289-0144
The XLogP value of 2.4171 suggests moderate lipophilicity, balancing water solubility and membrane permeability for K289-0144. The TPSA of 99.52 Ų falls within the moderate polarity range, balancing permeability and solubility for K289-0144. Following Lipinski's Rule of Five, K289-0144 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of K289-0144?
The CAS number of K289-0144 is 403728-99-4.
What is the molecular formula of K289-0144?
The molecular formula of K289-0144 is C22H23N3O5S.
What is the molecular weight of K289-0144?
The molecular weight of K289-0144 is 441.14 g/mol.
Where can I buy K289-0144?
You can request a quote for K289-0144 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for K289-0144?
Yes, KEHONG BIO provides custom synthesis services for K289-0144 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.