(Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide
TL;DR: (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide (CAS 403649-89-8) is a chemical compound with molecular formula C18H14ClFN4O and molecular weight 356.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(Z)-1-(4-chlorophenyl)ethylideneamino]-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide
Also Known As: (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide, N'-[(1Z)-1-(4-chlorophenyl)ethylidene]-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide, N-[(1Z)-2-(4-chlorophenyl)-1-azaprop-1-enyl][3-(4-fluorophenyl)pyrazol-5-yl]ca rboxamide, N-[(Z)-1-(4-chlorophenyl)ethylideneamino]-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide
| Molecular Formula | C18H14ClFN4O |
|---|---|
| Molecular Weight | 356.08 g/mol |
| LogP | 4.0232 |
| Topological Polar Surface Area | 70.14 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 356.084 |
| Heavy Atoms | 25 |
| Complexity | 917.0089 |
Chemical Identifiers
| CAS Number | 403649-89-8 |
|---|---|
| SMILES | C/C(=N/NC(=O)C1=CC(=NN1)C2=CC=C(C=C2)F)/C3=CC=C(C=C3)Cl |
Product Overview
(Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide (CAS 403649-89-8), with molecular formula C18H14ClFN4O and molecular weight 356.08 g/mol. IUPAC: N-[(Z)-1-(4-chlorophenyl)ethylideneamino]-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide.
Chemical Property Profile of (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide
Property Insights of (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide
The XLogP value of 4.0232 indicates that (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.14 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide. Following Lipinski's Rule of Five, (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide?
The CAS number of (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide is 403649-89-8.
What is the molecular formula of (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide?
The molecular formula of (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide is C18H14ClFN4O.
What is the molecular weight of (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide?
The molecular weight of (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide is 356.08 g/mol.
Where can I buy (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide?
You can request a quote for (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (Z)-N'-(1-(4-chlorophenyl)ethylidene)-3-(4-fluorophenyl)-1H-pyrazole-5-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.