![(4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione structure](/static/products/402/402961-52-8.png)
(4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione
TL;DR: (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione (CAS 402961-52-8) is a chemical compound with molecular formula C26H17F4NO3 and molecular weight 467.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-fluorophenyl)-4-hydroxy-3-[(E)-3-phenylprop-2-enoyl]-1-[3-(trifluoromethyl)phenyl]-2H-pyrrol-5-one
Also Known As: (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione, 2-(2-fluorophenyl)-4-hydroxy-3-[(E)-3-phenylprop-2-enoyl]-1-[3-(trifluoromethyl)phenyl]-2H-pyrrol-5-one, 4-cinnamoyl-5-(2-fluorophenyl)-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one
| Molecular Formula | C26H17F4NO3 |
|---|---|
| Molecular Weight | 467.11 g/mol |
| LogP | 6.027 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 467.11444 |
| Heavy Atoms | 34 |
| Complexity | 1312.876 |
Chemical Identifiers
| CAS Number | 402961-52-8 |
|---|---|
| SMILES | C1=CC=C(C=C1)/C=C/C(=O)C2=C(C(=O)N(C2C3=CC=CC=C3F)C4=CC=CC(=C4)C(F)(F)F)O |
Product Overview
(4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione (CAS 402961-52-8), with molecular formula C26H17F4NO3 and molecular weight 467.11 g/mol. IUPAC: 2-(2-fluorophenyl)-4-hydroxy-3-[(E)-3-phenylprop-2-enoyl]-1-[3-(trifluoromethyl)phenyl]-2H-pyrrol-5-one.
Chemical Property Profile of (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione
Property Insights of (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione
The XLogP value of 6.027 indicates that (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione?
The CAS number of (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione is 402961-52-8.
What is the molecular formula of (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione?
The molecular formula of (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione is C26H17F4NO3.
What is the molecular weight of (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione?
The molecular weight of (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione is 467.11 g/mol.
Where can I buy (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione?
You can request a quote for (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4Z)-5-(2-fluorophenyl)-4-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.