(Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide
TL;DR: (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide (CAS 402946-07-0) is a chemical compound with molecular formula C21H22N2OS and molecular weight 350.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[3,4-bis(4-methylphenyl)-1,3-thiazol-2-ylidene]-2-methylpropanamide
Also Known As: IFLab1_003974, (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide, F0856-0358, N-[(2Z)-3,4-bis(4-methylphenyl)-2,3-dihydro-1,3-thiazol-2-ylidene]-2-methylpropanamide, N-[3,4-bis(4-methylphenyl)-1,3-thiazol-2-ylidene]-2-methylpropanamide
| Molecular Formula | C21H22N2OS |
|---|---|
| Molecular Weight | 350.15 g/mol |
| LogP | 4.90594 |
| Topological Polar Surface Area | 34.36 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 350.1453 |
| Heavy Atoms | 25 |
| Complexity | 944.81116 |
Chemical Identifiers
| CAS Number | 402946-07-0 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=CSC(=NC(=O)C(C)C)N2C3=CC=C(C=C3)C |
Product Overview
(Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide (CAS 402946-07-0), with molecular formula C21H22N2OS and molecular weight 350.15 g/mol. IUPAC: N-[3,4-bis(4-methylphenyl)-1,3-thiazol-2-ylidene]-2-methylpropanamide.
Chemical Property Profile of (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide
Property Insights of (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide
The XLogP value of 4.90594 indicates that (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.36 Ų, (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide?
The CAS number of (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide is 402946-07-0.
What is the molecular formula of (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide?
The molecular formula of (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide is C21H22N2OS.
What is the molecular weight of (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide?
The molecular weight of (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide is 350.15 g/mol.
Where can I buy (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide?
You can request a quote for (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide?
Yes, KEHONG BIO provides custom synthesis services for (Z)-N-(3,4-di-p-tolylthiazol-2(3H)-ylidene)isobutyramide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.