4-Hydroxycyclophosphamide
TL;DR: 4-Hydroxycyclophosphamide (CAS 40277-05-2) is a chemical compound with molecular formula C7H15Cl2N2O3P and molecular weight 276.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2λ5-oxazaphosphinan-4-ol
Also Known As: 4-Hydroxycyclophosphamide, 4-Hydroxycytoxan, Cyclophosphamide metabolite, (R,S)-4-Hydroxy Cyclophosphamide, -4-HydroxyCyclophosphamide
| Molecular Formula | C7H15Cl2N2O3P |
|---|---|
| Molecular Weight | 276.02 g/mol |
| LogP | 0.2 |
| Topological Polar Surface Area | 61.8 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 276.01974 |
| Heavy Atoms | 15 |
| Complexity | 238.0 |
Chemical Identifiers
| CAS Number | 40277-05-2 |
|---|---|
| SMILES | C1COP(=O)(NC1O)N(CCCl)CCCl |
| InChIKey | RANONBLIHMVXAJ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
4-Hydroxycyclophosphamide (CAS 40277-05-2), with molecular formula C7H15Cl2N2O3P and molecular weight 276.02 g/mol. IUPAC: 2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2λ5-oxazaphosphinan-4-ol.
Chemical Property Profile of 4-Hydroxycyclophosphamide
Property Insights of 4-Hydroxycyclophosphamide
The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Hydroxycyclophosphamide. The TPSA of 61.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Hydroxycyclophosphamide. Following Lipinski's Rule of Five, 4-Hydroxycyclophosphamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Hydroxycyclophosphamide?
The CAS number of 4-Hydroxycyclophosphamide is 40277-05-2.
What is the molecular formula of 4-Hydroxycyclophosphamide?
The molecular formula of 4-Hydroxycyclophosphamide is C7H15Cl2N2O3P.
What is the molecular weight of 4-Hydroxycyclophosphamide?
The molecular weight of 4-Hydroxycyclophosphamide is 276.02 g/mol.
Where can I buy 4-Hydroxycyclophosphamide?
You can request a quote for 4-Hydroxycyclophosphamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Hydroxycyclophosphamide?
Yes, KEHONG BIO provides custom synthesis services for 4-Hydroxycyclophosphamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.