5-Fluoronicotinic Acid structure

5-Fluoronicotinic Acid

TL;DR: 5-Fluoronicotinic Acid (CAS 402-66-4) is a chemical compound with molecular formula C6H4FNO2 and molecular weight 141.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-fluoropyridine-3-carboxylic acid

Also Known As: 5-Fluoronicotinic acid, 5-fluoropyridine-3-carboxylic acid, 5-Fluoro-nicotinic acid, null, 5-Fluoro-3-pyridinecarboxylic acid

CAS: 402-66-4
Molecular Formula C6H4FNO2
Molecular Weight 141.02 g/mol
LogP 0.5
Topological Polar Surface Area 50.2 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 1
Exact Mass 141.02261
Heavy Atoms 10
Complexity 140.0

Chemical Identifiers

CAS Number 402-66-4
SMILES C1=C(C=NC=C1F)C(=O)O
InChIKey BXZSBDDOYIWMGC-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Food Additives (1 patents) Heterocyclic Building Blocks (38 patents) Pharmaceutical Intermediates (11 patents) Specialty Chemicals (2 patents)

Product Overview

5-Fluoronicotinic Acid (CAS 402-66-4), with molecular formula C6H4FNO2 and molecular weight 141.02 g/mol. IUPAC: 5-fluoropyridine-3-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 5-Fluoronicotinic Acid

XLogP
0.5
TPSA (Topological Polar Surface Area)
50.2
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
1
Heavy Atoms
10
Complexity
140.0
Exact Mass
141.02261
Monoisotopic Mass
141.02261
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5-Fluoronicotinic Acid

The XLogP value of 0.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Fluoronicotinic Acid. With a topological polar surface area (TPSA) of 50.2 Ų, 5-Fluoronicotinic Acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Fluoronicotinic Acid has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5-Fluoronicotinic Acid?

The CAS number of 5-Fluoronicotinic Acid is 402-66-4.

What is the molecular formula of 5-Fluoronicotinic Acid?

The molecular formula of 5-Fluoronicotinic Acid is C6H4FNO2.

What is the molecular weight of 5-Fluoronicotinic Acid?

The molecular weight of 5-Fluoronicotinic Acid is 141.02 g/mol.

Where can I buy 5-Fluoronicotinic Acid?

You can request a quote for 5-Fluoronicotinic Acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5-Fluoronicotinic Acid?

Yes, KEHONG BIO provides custom synthesis services for 5-Fluoronicotinic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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