1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol
TL;DR: 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol (CAS 401930-07-2) is a chemical compound with molecular formula C10H12F3N3O and molecular weight 247.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol
Also Known As: 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol, 1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol, Maybridge1_000401, METHYLCYANOCARBAMATE, 1-(4-Trifluoromethyl-pyrimidin-2-yl)-piperidin-4-ol
| Molecular Formula | C10H12F3N3O |
|---|---|
| Molecular Weight | 247.09 g/mol |
| LogP | 1.4565 |
| Topological Polar Surface Area | 49.25 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 247.09325 |
| Heavy Atoms | 17 |
| Complexity | 388.62766 |
Chemical Identifiers
| CAS Number | 401930-07-2 |
|---|---|
| SMILES | C1CN(CCC1O)C2=NC=CC(=N2)C(F)(F)F |
Product Overview
1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol (CAS 401930-07-2), with molecular formula C10H12F3N3O and molecular weight 247.09 g/mol. IUPAC: 1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-ol.
Chemical Property Profile of 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol
Property Insights of 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol
The XLogP value of 1.4565 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol. With a topological polar surface area (TPSA) of 49.25 Ų, 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol?
The CAS number of 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol is 401930-07-2.
What is the molecular formula of 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol?
The molecular formula of 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol is C10H12F3N3O.
What is the molecular weight of 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol?
The molecular weight of 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol is 247.09 g/mol.
Where can I buy 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol?
You can request a quote for 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol?
Yes, KEHONG BIO provides custom synthesis services for 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.