Z-L-p-Fluoro-Phe-chloromethylketone
TL;DR: Z-L-p-Fluoro-Phe-chloromethylketone (CAS 400771-48-4) is a chemical compound with molecular formula C18H17ClFNO3 and molecular weight 349.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
benzyl N-[(2S)-4-chloro-1-(4-fluorophenyl)-3-oxobutan-2-yl]carbamate
Also Known As: Z-L-p-Fluoro-Phe-chloromethylketone, Z-p-fluoro-Phe-chloromethylketone, Z-4-fluoro-L-phenylalanine chloromethylketone, 1-Methyl-4-(methylsulfinyl)benzene, acs.jmedchem.1c00409_ST.149
| Molecular Formula | C18H17ClFNO3 |
|---|---|
| Molecular Weight | 349.09 g/mol |
| LogP | 3.4711 |
| Topological Polar Surface Area | 55.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 7 |
| Exact Mass | 349.0881 |
| Heavy Atoms | 24 |
| Complexity | 676.42303 |
Chemical Identifiers
| CAS Number | 400771-48-4 |
|---|---|
| SMILES | C1=CC=C(C=C1)COC(=O)N[C@@H](CC2=CC=C(C=C2)F)C(=O)CCl |
Product Overview
Z-L-p-Fluoro-Phe-chloromethylketone (CAS 400771-48-4), with molecular formula C18H17ClFNO3 and molecular weight 349.09 g/mol. IUPAC: benzyl N-[(2S)-4-chloro-1-(4-fluorophenyl)-3-oxobutan-2-yl]carbamate.
Chemical Property Profile of Z-L-p-Fluoro-Phe-chloromethylketone
Property Insights of Z-L-p-Fluoro-Phe-chloromethylketone
The XLogP value of 3.4711 indicates that Z-L-p-Fluoro-Phe-chloromethylketone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.4 Ų, Z-L-p-Fluoro-Phe-chloromethylketone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Z-L-p-Fluoro-Phe-chloromethylketone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Z-L-p-Fluoro-Phe-chloromethylketone?
The CAS number of Z-L-p-Fluoro-Phe-chloromethylketone is 400771-48-4.
What is the molecular formula of Z-L-p-Fluoro-Phe-chloromethylketone?
The molecular formula of Z-L-p-Fluoro-Phe-chloromethylketone is C18H17ClFNO3.
What is the molecular weight of Z-L-p-Fluoro-Phe-chloromethylketone?
The molecular weight of Z-L-p-Fluoro-Phe-chloromethylketone is 349.09 g/mol.
Where can I buy Z-L-p-Fluoro-Phe-chloromethylketone?
You can request a quote for Z-L-p-Fluoro-Phe-chloromethylketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Z-L-p-Fluoro-Phe-chloromethylketone?
Yes, KEHONG BIO provides custom synthesis services for Z-L-p-Fluoro-Phe-chloromethylketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.