Amlodipine Impurity 16
TL;DR: Amlodipine Impurity 16 (CAS 400602-36-0) is a chemical compound with molecular formula C24H27ClN2O8 and molecular weight 506.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-4-[2-[[4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridin-2-yl]methoxy]ethylamino]-4-oxobut-2-enoic acid
Also Known As: Amlodipine Impurity 16, Amlodipine Impurity 90, Amlodipine Glucose Adduct 1, (Z)-4-((2-((4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl)methoxy)ethyl)amino)-4-oxobut-2-enoic acid
| Molecular Formula | C24H27ClN2O8 |
|---|---|
| Molecular Weight | 506.15 g/mol |
| LogP | 2.0646 |
| Topological Polar Surface Area | 140.26 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 11 |
| Exact Mass | 506.1456 |
| Heavy Atoms | 35 |
| Complexity | 1077.0374 |
Chemical Identifiers
| CAS Number | 400602-36-0 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCNC(=O)/C=C\C(=O)O |
Product Overview
Amlodipine Impurity 16 (CAS 400602-36-0), with molecular formula C24H27ClN2O8 and molecular weight 506.15 g/mol. IUPAC: (Z)-4-[2-[[4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridin-2-yl]methoxy]ethylamino]-4-oxobut-2-enoic acid.
Chemical Property Profile of Amlodipine Impurity 16
Property Insights of Amlodipine Impurity 16
The XLogP value of 2.0646 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Amlodipine Impurity 16. The TPSA of 140.26 Ų indicates high polarity, suggesting Amlodipine Impurity 16 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amlodipine Impurity 16 has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amlodipine Impurity 16?
The CAS number of Amlodipine Impurity 16 is 400602-36-0.
What is the molecular formula of Amlodipine Impurity 16?
The molecular formula of Amlodipine Impurity 16 is C24H27ClN2O8.
What is the molecular weight of Amlodipine Impurity 16?
The molecular weight of Amlodipine Impurity 16 is 506.15 g/mol.
Where can I buy Amlodipine Impurity 16?
You can request a quote for Amlodipine Impurity 16 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amlodipine Impurity 16?
Yes, KEHONG BIO provides custom synthesis services for Amlodipine Impurity 16 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.