8G-937
TL;DR: 8G-937 (CAS 400087-99-2) is a chemical compound with molecular formula C22H18F6N4O and molecular weight 468.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-N-phenylmethoxypiperidin-4-imine
Also Known As: 8G-937, 1-[5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-yl]tetrahydro-4(1H)-pyridinone O-benzyloxime, 4-Piperidinone,1-[5,7-bis -1,8-naphthyridin-2-yl]-,O- oxime, 1-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-N-phenylmethoxypiperidin-4-imine, 1-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-N-phenylmethoxy-piperidin-4-imine
| Molecular Formula | C22H18F6N4O |
|---|---|
| Molecular Weight | 468.14 g/mol |
| LogP | 5.8404 |
| Topological Polar Surface Area | 50.61 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 468.1385 |
| Heavy Atoms | 33 |
| Complexity | 1151.2451 |
Chemical Identifiers
| CAS Number | 400087-99-2 |
|---|---|
| SMILES | C1CN(CCC1=NOCC2=CC=CC=C2)C3=NC4=C(C=C3)C(=CC(=N4)C(F)(F)F)C(F)(F)F |
Product Overview
8G-937 (CAS 400087-99-2), with molecular formula C22H18F6N4O and molecular weight 468.14 g/mol. IUPAC: 1-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-N-phenylmethoxypiperidin-4-imine.
Chemical Property Profile of 8G-937
Property Insights of 8G-937
The XLogP value of 5.8404 indicates that 8G-937 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.61 Ų, 8G-937 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8G-937 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8G-937?
The CAS number of 8G-937 is 400087-99-2.
What is the molecular formula of 8G-937?
The molecular formula of 8G-937 is C22H18F6N4O.
What is the molecular weight of 8G-937?
The molecular weight of 8G-937 is 468.14 g/mol.
Where can I buy 8G-937?
You can request a quote for 8G-937 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8G-937?
Yes, KEHONG BIO provides custom synthesis services for 8G-937 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.