![5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile structure](/static/products/4000/400087-66-3.webp)
5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile
TL;DR: 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile (CAS 400087-66-3) is a chemical compound with molecular formula C11H7F3N4S and molecular weight 284.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile
Also Known As: 5-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile, 8F-920, 5-amino-2-{[3-(trifluoromethyl)phenyl]amino}-1,3-thiazole-4-carbonitrile
| Molecular Formula | C11H7F3N4S |
|---|---|
| Molecular Weight | 284.03 g/mol |
| LogP | 3.35938 |
| Topological Polar Surface Area | 74.73 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 284.03436 |
| Heavy Atoms | 19 |
| Complexity | 642.12036 |
Chemical Identifiers
| CAS Number | 400087-66-3 |
|---|---|
| SMILES | C1=CC(=CC(=C1)NC2=NC(=C(S2)N)C#N)C(F)(F)F |
Product Overview
5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile (CAS 400087-66-3), with molecular formula C11H7F3N4S and molecular weight 284.03 g/mol. IUPAC: 5-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile.
Chemical Property Profile of 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile
Property Insights of 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile
The XLogP value of 3.35938 indicates that 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 74.73 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile. Following Lipinski's Rule of Five, 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile?
The CAS number of 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile is 400087-66-3.
What is the molecular formula of 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile?
The molecular formula of 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile is C11H7F3N4S.
What is the molecular weight of 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile?
The molecular weight of 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile is 284.03 g/mol.
Where can I buy 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile?
You can request a quote for 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile?
Yes, KEHONG BIO provides custom synthesis services for 5-Amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazole-4-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.