N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide
TL;DR: N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide (CAS 400079-01-8) is a chemical compound with molecular formula C16H11F2N3OS and molecular weight 331.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2,4-difluorophenyl)-4-methyl-2-pyridin-2-yl-1,3-thiazole-5-carboxamide
Also Known As: N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide, N-(2,4-difluorophenyl)-4-methyl-2-(pyridin-2-yl)-1,3-thiazole-5-carboxamide, n-(2,4-Difluorophenyl)-4-methyl-2-(pyridin-2-yl)thiazole-5-carboxamide, N-(2,4-difluorophenyl)-4-methyl-2-pyridin-2-yl-1,3-thiazole-5-carboxamide
| Molecular Formula | C16H11F2N3OS |
|---|---|
| Molecular Weight | 331.06 g/mol |
| LogP | 4.04402 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 331.05908 |
| Heavy Atoms | 23 |
| Complexity | 865.01685 |
Chemical Identifiers
| CAS Number | 400079-01-8 |
|---|---|
| SMILES | CC1=C(SC(=N1)C2=CC=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F |
Product Overview
N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide (CAS 400079-01-8), with molecular formula C16H11F2N3OS and molecular weight 331.06 g/mol. IUPAC: N-(2,4-difluorophenyl)-4-methyl-2-pyridin-2-yl-1,3-thiazole-5-carboxamide.
Chemical Property Profile of N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide
Property Insights of N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide
The XLogP value of 4.04402 indicates that N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide?
The CAS number of N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide is 400079-01-8.
What is the molecular formula of N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide?
The molecular formula of N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide is C16H11F2N3OS.
What is the molecular weight of N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide?
The molecular weight of N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide is 331.06 g/mol.
Where can I buy N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide?
You can request a quote for N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(2,4-difluorophenyl)-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.