![3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide structure](/static/products/4000/400077-91-0.webp)
3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide
TL;DR: 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide (CAS 400077-91-0) is a chemical compound with molecular formula C10H8ClF3N2O and molecular weight 264.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide
Also Known As: 3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-methylprop-2-enamide, 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylacrylamide
| Molecular Formula | C10H8ClF3N2O |
|---|---|
| Molecular Weight | 264.03 g/mol |
| LogP | 2.513 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 264.0277 |
| Heavy Atoms | 17 |
| Complexity | 457.3545 |
Chemical Identifiers
| CAS Number | 400077-91-0 |
|---|---|
| SMILES | CNC(=O)C=CC1=C(C=C(C=N1)C(F)(F)F)Cl |
Product Overview
3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide (CAS 400077-91-0), with molecular formula C10H8ClF3N2O and molecular weight 264.03 g/mol. IUPAC: 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide.
Chemical Property Profile of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide
Property Insights of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide
The XLogP value of 2.513 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide. With a topological polar surface area (TPSA) of 41.99 Ų, 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide?
The CAS number of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide is 400077-91-0.
What is the molecular formula of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide?
The molecular formula of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide is C10H8ClF3N2O.
What is the molecular weight of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide?
The molecular weight of 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide is 264.03 g/mol.
Where can I buy 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide?
You can request a quote for 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for 3-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-methylprop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.