1F-378S
TL;DR: 1F-378S (CAS 400077-85-2) is a chemical compound with molecular formula C19H11Cl4N3O and molecular weight 436.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(2,5-dichlorophenyl)-2-[(2,6-dichlorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-one
Also Known As: 1F-378S, 2-(2,6-dichlorobenzyl)-1-(2,5-dichlorophenyl)-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-one, 1-(2,5-dichlorophenyl)-2-[(2,6-dichlorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-one, 1-(2,5-dichlorophenyl)-2-[(2,6-dichlorophenyl)methyl]-1H,2H,3H-pyrazolo[3,4-b]pyridin-3-one
| Molecular Formula | C19H11Cl4N3O |
|---|---|
| Molecular Weight | 436.97 g/mol |
| LogP | 5.8491 |
| Topological Polar Surface Area | 39.82 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 436.96564 |
| Heavy Atoms | 27 |
| Complexity | 1209.3275 |
Chemical Identifiers
| CAS Number | 400077-85-2 |
|---|---|
| SMILES | C1=CC(=C(C(=C1)Cl)CN2C(=O)C3=C(N2C4=C(C=CC(=C4)Cl)Cl)N=CC=C3)Cl |
Product Overview
1F-378S (CAS 400077-85-2), with molecular formula C19H11Cl4N3O and molecular weight 436.97 g/mol. IUPAC: 1-(2,5-dichlorophenyl)-2-[(2,6-dichlorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-one.
Chemical Property Profile of 1F-378S
Property Insights of 1F-378S
The XLogP value of 5.8491 indicates that 1F-378S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 39.82 Ų, 1F-378S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1F-378S has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1F-378S?
The CAS number of 1F-378S is 400077-85-2.
What is the molecular formula of 1F-378S?
The molecular formula of 1F-378S is C19H11Cl4N3O.
What is the molecular weight of 1F-378S?
The molecular weight of 1F-378S is 436.97 g/mol.
Where can I buy 1F-378S?
You can request a quote for 1F-378S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1F-378S?
Yes, KEHONG BIO provides custom synthesis services for 1F-378S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.