4-(Hydroxymethyl)colchicine
TL;DR: 4-(Hydroxymethyl)colchicine (CAS 3986-03-6) is a chemical compound with molecular formula C23H27NO7 and molecular weight 429.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-4-(hydroxymethyl)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: 4-(Hydroxymethyl)colchicine, 4-Hmclc, Colchicine, 4-(hydroxymethyl)-, J2.107.955C, N-[(7S)-4-(hydroxymethyl)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
| Molecular Formula | C23H27NO7 |
|---|---|
| Molecular Weight | 429.18 g/mol |
| LogP | 0.1 |
| Topological Polar Surface Area | 103.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 429.17874 |
| Heavy Atoms | 31 |
| Complexity | 787.0 |
Chemical Identifiers
| CAS Number | 3986-03-6 |
|---|---|
| SMILES | CC(=O)N[C@H]1CCC2=C(C(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC)CO |
| InChIKey | XOAUTVKFAKCYKZ-KRWDZBQOSA-N |
Product Overview
4-(Hydroxymethyl)colchicine (CAS 3986-03-6), with molecular formula C23H27NO7 and molecular weight 429.18 g/mol. IUPAC: N-[(7S)-4-(hydroxymethyl)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of 4-(Hydroxymethyl)colchicine
Property Insights of 4-(Hydroxymethyl)colchicine
The XLogP value of 0.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(Hydroxymethyl)colchicine. The TPSA of 103.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(Hydroxymethyl)colchicine. Following Lipinski's Rule of Five, 4-(Hydroxymethyl)colchicine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(Hydroxymethyl)colchicine?
The CAS number of 4-(Hydroxymethyl)colchicine is 3986-03-6.
What is the molecular formula of 4-(Hydroxymethyl)colchicine?
The molecular formula of 4-(Hydroxymethyl)colchicine is C23H27NO7.
What is the molecular weight of 4-(Hydroxymethyl)colchicine?
The molecular weight of 4-(Hydroxymethyl)colchicine is 429.18 g/mol.
Where can I buy 4-(Hydroxymethyl)colchicine?
You can request a quote for 4-(Hydroxymethyl)colchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(Hydroxymethyl)colchicine?
Yes, KEHONG BIO provides custom synthesis services for 4-(Hydroxymethyl)colchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.