US10849901, Compound 136
TL;DR: US10849901, Compound 136 (CAS 398471-20-0) is a chemical compound with molecular formula C28H20FN3S2 and molecular weight 481.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-4-(4-phenylphenyl)-1,3-thiazole
Also Known As: US10849901, Compound 136, A1558/0067891, 2-[3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-4-(4-phenylphenyl)-1,3-thiazole, 4-(biphenyl-4-yl)-2-[5-(4-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazole, 4-[1,1'-biphenyl]-4-yl-2-[5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazol-1-yl]-1,3-thiazole
| Molecular Formula | C28H20FN3S2 |
|---|---|
| Molecular Weight | 481.11 g/mol |
| LogP | 8.0334 |
| Topological Polar Surface Area | 28.49 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 481.10828 |
| Heavy Atoms | 34 |
| Complexity | 1423.5771 |
Chemical Identifiers
| CAS Number | 398471-20-0 |
|---|---|
| SMILES | C1C(N(N=C1C2=CC=CS2)C3=NC(=CS3)C4=CC=C(C=C4)C5=CC=CC=C5)C6=CC=C(C=C6)F |
Product Overview
US10849901, Compound 136 (CAS 398471-20-0), with molecular formula C28H20FN3S2 and molecular weight 481.11 g/mol. IUPAC: 2-[3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-4-(4-phenylphenyl)-1,3-thiazole.
Chemical Property Profile of US10849901, Compound 136
Property Insights of US10849901, Compound 136
The XLogP value of 8.0334 indicates that US10849901, Compound 136 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.49 Ų, US10849901, Compound 136 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, US10849901, Compound 136 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of US10849901, Compound 136?
The CAS number of US10849901, Compound 136 is 398471-20-0.
What is the molecular formula of US10849901, Compound 136?
The molecular formula of US10849901, Compound 136 is C28H20FN3S2.
What is the molecular weight of US10849901, Compound 136?
The molecular weight of US10849901, Compound 136 is 481.11 g/mol.
Where can I buy US10849901, Compound 136?
You can request a quote for US10849901, Compound 136 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for US10849901, Compound 136?
Yes, KEHONG BIO provides custom synthesis services for US10849901, Compound 136 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.