![3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride structure](/static/products/3972/397-28-4.webp)
3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride
TL;DR: 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride (CAS 397-28-4) is a chemical compound with molecular formula C13H11ClF3N and molecular weight 273.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[3-(trifluoromethyl)phenyl]aniline;hydrochloride
Also Known As: 3'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride, 3'-trifluoromethylbiphenyl-4-ylamine hydrochloride, 4-[3-(trifluoromethyl)phenyl]aniline Hydrochloride, 4-[3-(trifluoromethyl)phenyl]aniline;hydrochloride, 3'-Trifluoromethyl-biphenyl-4-ylamine hydro-chloride
| Molecular Formula | C13H11ClF3N |
|---|---|
| Molecular Weight | 273.05 g/mol |
| LogP | 4.3764 |
| Topological Polar Surface Area | 26.02 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 273.05322 |
| Heavy Atoms | 18 |
| Complexity | 520.5047 |
Chemical Identifiers
| CAS Number | 397-28-4 |
|---|---|
| SMILES | C1=CC(=CC(=C1)C(F)(F)F)C2=CC=C(C=C2)N.Cl |
Product Overview
3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride (CAS 397-28-4), with molecular formula C13H11ClF3N and molecular weight 273.05 g/mol. IUPAC: 4-[3-(trifluoromethyl)phenyl]aniline;hydrochloride.
Chemical Property Profile of 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride
Property Insights of 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride
The XLogP value of 4.3764 indicates that 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.02 Ų, 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride?
The CAS number of 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride is 397-28-4.
What is the molecular formula of 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride?
The molecular formula of 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride is C13H11ClF3N.
What is the molecular weight of 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride?
The molecular weight of 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride is 273.05 g/mol.
Where can I buy 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride?
You can request a quote for 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for 3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.