TH136
TL;DR: TH136 (CAS 396722-46-6) is a chemical compound with molecular formula C24H21N3OS and molecular weight 399.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]naphthalene-2-carboxamide
Also Known As: TH136, F0778-0256, N-[2-(2,4-dimethylphenyl)-2H,4H,6H-thieno[3,4-c]pyrazol-3-yl]naphthalene-2-carboxamide, N-(2-(2,4-dimethylphenyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-naphthamide, N-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]naphthalene-2-carboxamide
| Molecular Formula | C24H21N3OS |
|---|---|
| Molecular Weight | 399.14 g/mol |
| LogP | 5.64144 |
| Topological Polar Surface Area | 46.92 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 399.14053 |
| Heavy Atoms | 29 |
| Complexity | 1258.4584 |
Chemical Identifiers
| CAS Number | 396722-46-6 |
|---|---|
| SMILES | CC1=CC(=C(C=C1)N2C(=C3CSCC3=N2)NC(=O)C4=CC5=CC=CC=C5C=C4)C |
Product Overview
TH136 (CAS 396722-46-6), with molecular formula C24H21N3OS and molecular weight 399.14 g/mol. IUPAC: N-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]naphthalene-2-carboxamide.
Chemical Property Profile of TH136
Property Insights of TH136
The XLogP value of 5.64144 indicates that TH136 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.92 Ų, TH136 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, TH136 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of TH136?
The CAS number of TH136 is 396722-46-6.
What is the molecular formula of TH136?
The molecular formula of TH136 is C24H21N3OS.
What is the molecular weight of TH136?
The molecular weight of TH136 is 399.14 g/mol.
Where can I buy TH136?
You can request a quote for TH136 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for TH136?
Yes, KEHONG BIO provides custom synthesis services for TH136 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.