TH123 structure

TH123

TL;DR: TH123 (CAS 396720-67-5) is a chemical compound with molecular formula C20H18N4O3S and molecular weight 394.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-4-nitrobenzamide

Also Known As: TH123, F0778-0100, N-(2-(2,4-dimethylphenyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-4-nitrobenzamide, N-[2-(2,4-dimethylphenyl)-2H,4H,6H-thieno[3,4-c]pyrazol-3-yl]-4-nitrobenzamide, N-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-4-nitrobenzamide

CAS: 396720-67-5
Molecular Formula C20H18N4O3S
Molecular Weight 394.11 g/mol
LogP 4.39644
Topological Polar Surface Area 90.06 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 4
Exact Mass 394.10995
Heavy Atoms 28
Complexity 1089.5754

Chemical Identifiers

CAS Number 396720-67-5
SMILES CC1=CC(=C(C=C1)N2C(=C3CSCC3=N2)NC(=O)C4=CC=C(C=C4)[N+](=O)[O-])C

Product Overview

TH123 (CAS 396720-67-5), with molecular formula C20H18N4O3S and molecular weight 394.11 g/mol. IUPAC: N-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-4-nitrobenzamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of TH123

XLogP
4.39644
TPSA (Topological Polar Surface Area)
90.06
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
28
Complexity
1089.5754
Exact Mass
394.10995
Monoisotopic Mass
394.10995
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of TH123

The XLogP value of 4.39644 indicates that TH123 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 90.06 Ų falls within the moderate polarity range, balancing permeability and solubility for TH123. Following Lipinski's Rule of Five, TH123 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of TH123?

The CAS number of TH123 is 396720-67-5.

What is the molecular formula of TH123?

The molecular formula of TH123 is C20H18N4O3S.

What is the molecular weight of TH123?

The molecular weight of TH123 is 394.11 g/mol.

Where can I buy TH123?

You can request a quote for TH123 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for TH123?

Yes, KEHONG BIO provides custom synthesis services for TH123 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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