16-Methylene-17 alpha-hydroxyprogesterone
TL;DR: 16-Methylene-17 alpha-hydroxyprogesterone (CAS 3965-17-1) is a chemical compound with molecular formula C22H30O3 and molecular weight 342.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-16-methylidene-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthren-3-one
Also Known As: 16-Methylene-17alpha-hydroxyprogesterone, 16-methylene-17, A-hydroxyprogesterone, 16-methylene-17 Alpha-hydroxyprogesterone, Pregn-4-ene-3,20-dione, 17-hydroxy-16-methylene-
| Molecular Formula | C22H30O3 |
|---|---|
| Molecular Weight | 342.22 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 54.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 342.21948 |
| Heavy Atoms | 25 |
| Complexity | 704.0 |
Chemical Identifiers
| CAS Number | 3965-17-1 |
|---|---|
| SMILES | CC(=O)[C@]1(C(=C)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O |
| InChIKey | CAHSRYQWSFJFGS-GUCLMQHLSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
16-Methylene-17 alpha-hydroxyprogesterone (CAS 3965-17-1), with molecular formula C22H30O3 and molecular weight 342.22 g/mol. IUPAC: (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-16-methylidene-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 16-Methylene-17 alpha-hydroxyprogesterone
Property Insights of 16-Methylene-17 alpha-hydroxyprogesterone
The XLogP value of 3.2 indicates that 16-Methylene-17 alpha-hydroxyprogesterone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.4 Ų, 16-Methylene-17 alpha-hydroxyprogesterone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 16-Methylene-17 alpha-hydroxyprogesterone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 16-Methylene-17 alpha-hydroxyprogesterone?
The CAS number of 16-Methylene-17 alpha-hydroxyprogesterone is 3965-17-1.
What is the molecular formula of 16-Methylene-17 alpha-hydroxyprogesterone?
The molecular formula of 16-Methylene-17 alpha-hydroxyprogesterone is C22H30O3.
What is the molecular weight of 16-Methylene-17 alpha-hydroxyprogesterone?
The molecular weight of 16-Methylene-17 alpha-hydroxyprogesterone is 342.22 g/mol.
Where can I buy 16-Methylene-17 alpha-hydroxyprogesterone?
You can request a quote for 16-Methylene-17 alpha-hydroxyprogesterone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 16-Methylene-17 alpha-hydroxyprogesterone?
Yes, KEHONG BIO provides custom synthesis services for 16-Methylene-17 alpha-hydroxyprogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.