2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate structure

2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate

TL;DR: 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate (CAS 39642-60-9) is a chemical compound with molecular formula C22H32F2O2 and molecular weight 366.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(1S,2S,4R,6S,8S,11R,12S,15S,16S)-5,5-difluoro-2,16-dimethyl-15-pentacyclo[9.7.0.02,8.04,6.012,16]octadecanyl] acetate

Also Known As: 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate, J2.793.868J, A,3, A-(difluoromethylene)-5, A-androstan-17

CAS: 39642-60-9
Molecular Formula C22H32F2O2
Molecular Weight 366.24 g/mol
LogP 6.0
Topological Polar Surface Area 26.3 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 366.23703
Heavy Atoms 26
Complexity 634.0

Chemical Identifiers

CAS Number 39642-60-9
SMILES CC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@@H]5[C@H](C4)C5(F)F)C)C
InChIKey BRZLCOPFROJRBE-WMFBMNODSA-N

Product Overview

2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate (CAS 39642-60-9), with molecular formula C22H32F2O2 and molecular weight 366.24 g/mol. IUPAC: [(1S,2S,4R,6S,8S,11R,12S,15S,16S)-5,5-difluoro-2,16-dimethyl-15-pentacyclo[9.7.0.02,8.04,6.012,16]octadecanyl] acetate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate

XLogP
6.0
TPSA (Topological Polar Surface Area)
26.3
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
26
Complexity
634.0
Exact Mass
366.23703
Monoisotopic Mass
366.23703
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate

The XLogP value of 6.0 indicates that 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.3 Ų, 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate?

The CAS number of 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate is 39642-60-9.

What is the molecular formula of 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate?

The molecular formula of 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate is C22H32F2O2.

What is the molecular weight of 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate?

The molecular weight of 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate is 366.24 g/mol.

Where can I buy 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate?

You can request a quote for 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate?

Yes, KEHONG BIO provides custom synthesis services for 2alpha,3alpha-(Difluoromethylene)-5alpha-androstan-17beta-ol, acetate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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