Felodipine Impurity 8
TL;DR: Felodipine Impurity 8 (CAS 39562-06-6) is a chemical compound with molecular formula C18H20ClNO4 and molecular weight 349.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-O-ethyl 3-O-methyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Felodipine Impurity 8, Amlodipine Impurity 48, Amlodipine Impurity 50, BAS 00156991, 3-Ethyl 5-methyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
| Molecular Formula | C18H20ClNO4 |
|---|---|
| Molecular Weight | 349.11 g/mol |
| LogP | 3.3109 |
| Topological Polar Surface Area | 64.63 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 349.1081 |
| Heavy Atoms | 24 |
| Complexity | 736.28925 |
Chemical Identifiers
| CAS Number | 39562-06-6 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)C |
Product Overview
Felodipine Impurity 8 (CAS 39562-06-6), with molecular formula C18H20ClNO4 and molecular weight 349.11 g/mol. IUPAC: 5-O-ethyl 3-O-methyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Felodipine Impurity 8
Property Insights of Felodipine Impurity 8
The XLogP value of 3.3109 indicates that Felodipine Impurity 8 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.63 Ų falls within the moderate polarity range, balancing permeability and solubility for Felodipine Impurity 8. Following Lipinski's Rule of Five, Felodipine Impurity 8 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Felodipine Impurity 8?
The CAS number of Felodipine Impurity 8 is 39562-06-6.
What is the molecular formula of Felodipine Impurity 8?
The molecular formula of Felodipine Impurity 8 is C18H20ClNO4.
What is the molecular weight of Felodipine Impurity 8?
The molecular weight of Felodipine Impurity 8 is 349.11 g/mol.
Where can I buy Felodipine Impurity 8?
You can request a quote for Felodipine Impurity 8 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Felodipine Impurity 8?
Yes, KEHONG BIO provides custom synthesis services for Felodipine Impurity 8 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.