4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine
TL;DR: 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine (CAS 395090-52-5) is a chemical compound with molecular formula C11H10FN3O2S and molecular weight 267.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(3-fluorophenyl)-5-methylsulfonylpyrimidin-2-amine
Also Known As: Peakdale1_000571, 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine, 4-(3-Fluoro-phenyl)-5-methanesulfonyl-pyrimidin-2-ylamine, 4-(3-fluorophenyl)-5-methylsulfonylpyrimidin-2-amine
| Molecular Formula | C11H10FN3O2S |
|---|---|
| Molecular Weight | 267.05 g/mol |
| LogP | 1.2684 |
| Topological Polar Surface Area | 85.94 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 267.0478 |
| Heavy Atoms | 18 |
| Complexity | 701.1846 |
Chemical Identifiers
| CAS Number | 395090-52-5 |
|---|---|
| SMILES | CS(=O)(=O)C1=CN=C(N=C1C2=CC(=CC=C2)F)N |
Product Overview
4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine (CAS 395090-52-5), with molecular formula C11H10FN3O2S and molecular weight 267.05 g/mol. IUPAC: 4-(3-fluorophenyl)-5-methylsulfonylpyrimidin-2-amine.
Chemical Property Profile of 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine
Property Insights of 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine
The XLogP value of 1.2684 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine. The TPSA of 85.94 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine. Following Lipinski's Rule of Five, 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine?
The CAS number of 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine is 395090-52-5.
What is the molecular formula of 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine?
The molecular formula of 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine is C11H10FN3O2S.
What is the molecular weight of 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine?
The molecular weight of 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine is 267.05 g/mol.
Where can I buy 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine?
You can request a quote for 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-(3-Fluorophenyl)-5-(methylsulfonyl)pyrimidin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.