Pyroglutamyl-phenylalanyl-prolinamide
TL;DR: Pyroglutamyl-phenylalanyl-prolinamide (CAS 39494-12-7) is a chemical compound with molecular formula C19H24N4O4 and molecular weight 372.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Pglu-phe-pro-NH2, Pyroglutamyl-phenylalanyl-prolinamide, [Phe2]-TRH, Pyroglutamyl-Phe-Pro-NH2, Pyroglutamyl-phenylalanyl-proline amide
| Molecular Formula | C19H24N4O4 |
|---|---|
| Molecular Weight | 372.18 g/mol |
| LogP | -0.6 |
| Topological Polar Surface Area | 122.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 372.17975 |
| Heavy Atoms | 27 |
| Complexity | 603.0 |
Chemical Identifiers
| CAS Number | 39494-12-7 |
|---|---|
| SMILES | C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)N |
| InChIKey | ZETOYWKJNIJFCR-KKUMJFAQSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Pyroglutamyl-phenylalanyl-prolinamide (CAS 39494-12-7), with molecular formula C19H24N4O4 and molecular weight 372.18 g/mol. IUPAC: (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of Pyroglutamyl-phenylalanyl-prolinamide
Property Insights of Pyroglutamyl-phenylalanyl-prolinamide
The XLogP value of -0.6 indicates that Pyroglutamyl-phenylalanyl-prolinamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 122.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Pyroglutamyl-phenylalanyl-prolinamide. Following Lipinski's Rule of Five, Pyroglutamyl-phenylalanyl-prolinamide has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyroglutamyl-phenylalanyl-prolinamide?
The CAS number of Pyroglutamyl-phenylalanyl-prolinamide is 39494-12-7.
What is the molecular formula of Pyroglutamyl-phenylalanyl-prolinamide?
The molecular formula of Pyroglutamyl-phenylalanyl-prolinamide is C19H24N4O4.
What is the molecular weight of Pyroglutamyl-phenylalanyl-prolinamide?
The molecular weight of Pyroglutamyl-phenylalanyl-prolinamide is 372.18 g/mol.
Where can I buy Pyroglutamyl-phenylalanyl-prolinamide?
You can request a quote for Pyroglutamyl-phenylalanyl-prolinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyroglutamyl-phenylalanyl-prolinamide?
Yes, KEHONG BIO provides custom synthesis services for Pyroglutamyl-phenylalanyl-prolinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.