Nigellone structure

Nigellone

TL;DR: Nigellone (CAS 39461-20-6) is a chemical compound with molecular formula C20H24O4 and molecular weight 328.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4b,8b-dimethyl-3,7-di(propan-2-yl)-4a,8a-dihydrobiphenylene-1,4,5,8-tetrone

Also Known As: Dithymoquinone, Nigellone, 4b,8b-dimethyl-3,7-di(propan-2-yl)-4a,8a-dihydrobiphenylene-1,4,5,8-tetrone, 2,6-Diisopropyl-4a,8a-dimethylbiphenylene-1,4,5,8(4aH,4bH,8aH,8bH)-tetrone, 4a,4b,8a,8b-Tetrahydro-2,6-diisopropyl-4a,8a-dimethylbiphenylene-1,4,5,8-tetraone

CAS: 39461-20-6
Molecular Formula C20H24O4
Molecular Weight 328.17 g/mol
LogP 2.1
Topological Polar Surface Area 68.3 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 328.16745
Heavy Atoms 24
Complexity 684.0

Chemical Identifiers

CAS Number 39461-20-6
SMILES CC(C)C1=CC(=O)C2(C(C1=O)C3(C2C(=O)C(=CC3=O)C(C)C)C)C
InChIKey FPRGRROJPRIHJP-UHFFFAOYSA-N

Product Overview

Nigellone (CAS 39461-20-6), with molecular formula C20H24O4 and molecular weight 328.17 g/mol. IUPAC: 4b,8b-dimethyl-3,7-di(propan-2-yl)-4a,8a-dihydrobiphenylene-1,4,5,8-tetrone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Nigellone

XLogP
2.1
TPSA (Topological Polar Surface Area)
68.3
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
24
Complexity
684.0
Exact Mass
328.16745
Monoisotopic Mass
328.16745
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Nigellone

The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nigellone. The TPSA of 68.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Nigellone. Following Lipinski's Rule of Five, Nigellone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Nigellone?

The CAS number of Nigellone is 39461-20-6.

What is the molecular formula of Nigellone?

The molecular formula of Nigellone is C20H24O4.

What is the molecular weight of Nigellone?

The molecular weight of Nigellone is 328.17 g/mol.

Where can I buy Nigellone?

You can request a quote for Nigellone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Nigellone?

Yes, KEHONG BIO provides custom synthesis services for Nigellone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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