3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide structure

3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide

TL;DR: 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide (CAS 394239-15-7) is a chemical compound with molecular formula C26H20ClFN4OS and molecular weight 490.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-(6-chloro-2-oxo-4-phenyl-1H-quinolin-3-yl)-3-(2-fluorophenyl)-N-methyl-3,4-dihydropyrazole-2-carbothioamide

Also Known As: 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide, (3E)-3-(6-chloro-2-oxo-4-phenylquinolin-3-ylidene)-5-(2-fluorophenyl)-N-methylpyrazolidine-1-carbothioamide, (3Z)-3-(6-chloro-2-oxo-4-phenylquinolin-3-ylidene)-5-(2-fluorophenyl)-N-methylpyrazolidine-1-carbothioamide, 3-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide, 3-(6-chloro-2-oxo-4-phenylquinolin-3-ylidene)-5-(2-fluorophenyl)-N-methylpyrazolidine-1-carbothioamide

CAS: 394239-15-7
Molecular Formula C26H20ClFN4OS
Molecular Weight 490.10 g/mol
LogP 5.643
Topological Polar Surface Area 60.49 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 3
Exact Mass 490.10303
Heavy Atoms 34
Complexity 1502.2053

Chemical Identifiers

CAS Number 394239-15-7
SMILES CNC(=S)N1C(CC(=N1)C2=C(C3=C(C=CC(=C3)Cl)NC2=O)C4=CC=CC=C4)C5=CC=CC=C5F

Product Overview

3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide (CAS 394239-15-7), with molecular formula C26H20ClFN4OS and molecular weight 490.10 g/mol. IUPAC: 5-(6-chloro-2-oxo-4-phenyl-1H-quinolin-3-yl)-3-(2-fluorophenyl)-N-methyl-3,4-dihydropyrazole-2-carbothioamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide

XLogP
5.643
TPSA (Topological Polar Surface Area)
60.49
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
3
Heavy Atoms
34
Complexity
1502.2053
Exact Mass
490.10303
Monoisotopic Mass
490.10303
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide

The XLogP value of 5.643 indicates that 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.49 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide. Following Lipinski's Rule of Five, 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide?

The CAS number of 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide is 394239-15-7.

What is the molecular formula of 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide?

The molecular formula of 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide is C26H20ClFN4OS.

What is the molecular weight of 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide?

The molecular weight of 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide is 490.10 g/mol.

Where can I buy 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide?

You can request a quote for 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide?

Yes, KEHONG BIO provides custom synthesis services for 3-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-5-(2-fluorophenyl)-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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