5-HT2B antagonist-1 structure

5-HT2B antagonist-1

TL;DR: 5-HT2B antagonist-1 (CAS 393129-91-4) is a chemical compound with molecular formula C22H28N4O2S2 and molecular weight 444.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[4-(4-tert-butylphenyl)sulfonylpiperazin-1-yl]-5,6-dimethylthieno[2,3-d]pyrimidine

Also Known As: 5-HT2B antagonist-1, 4-[4-(4-tert-butylphenyl)sulfonylpiperazin-1-yl]-5,6-dimethylthieno[2,3-d]pyrimidine, 4-(4-((4-(tert-Butyl)phenyl)sulfonyl)piperazin-1-yl)-5,6-dimethylthieno[2,3-d]pyrimidine, 4-[4-(4-tert-butylphenyl)sulfonylpiperazin-1-yl]-5,6-dimethyl-thieno[2,3-d]pyrimidine, 4-[4-(4-tert-Butylbenzene-1-sulfonyl)piperazin-1-yl]-5,6-dimethylthieno[2,3-d]pyrimidine

CAS: 393129-91-4
Molecular Formula C22H28N4O2S2
Molecular Weight 444.17 g/mol
LogP 4.11654
Topological Polar Surface Area 66.4 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 3
Exact Mass 444.16537
Heavy Atoms 30
Complexity 1170.3082

Chemical Identifiers

CAS Number 393129-91-4
SMILES CC1=C(SC2=NC=NC(=C12)N3CCN(CC3)S(=O)(=O)C4=CC=C(C=C4)C(C)(C)C)C

Product Overview

5-HT2B antagonist-1 (CAS 393129-91-4), with molecular formula C22H28N4O2S2 and molecular weight 444.17 g/mol. IUPAC: 4-[4-(4-tert-butylphenyl)sulfonylpiperazin-1-yl]-5,6-dimethylthieno[2,3-d]pyrimidine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 5-HT2B antagonist-1

XLogP
4.11654
TPSA (Topological Polar Surface Area)
66.4
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
3
Heavy Atoms
30
Complexity
1170.3082
Exact Mass
444.16537
Monoisotopic Mass
444.16537
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 5-HT2B antagonist-1

The XLogP value of 4.11654 indicates that 5-HT2B antagonist-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-HT2B antagonist-1. Following Lipinski's Rule of Five, 5-HT2B antagonist-1 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 5-HT2B antagonist-1?

The CAS number of 5-HT2B antagonist-1 is 393129-91-4.

What is the molecular formula of 5-HT2B antagonist-1?

The molecular formula of 5-HT2B antagonist-1 is C22H28N4O2S2.

What is the molecular weight of 5-HT2B antagonist-1?

The molecular weight of 5-HT2B antagonist-1 is 444.17 g/mol.

Where can I buy 5-HT2B antagonist-1?

You can request a quote for 5-HT2B antagonist-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 5-HT2B antagonist-1?

Yes, KEHONG BIO provides custom synthesis services for 5-HT2B antagonist-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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